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Contributor

Shackleford, Terry (Faculty Mentor)

Digital Publisher

Digital Commons at St. Mary's

Publication Date

Spring 2026

Keywords

Cell biology, Ewing Sarcoma, Pediatric cancer

Description

Ewing sarcoma is an aggressive pediatric cancer driven by abnormal gene expression caused by the EWS-FLI1 fusion protein

Usually treated with intensive treatments such as chemotherapy and radiation

Outcomes remain poor for metastatic disease, highlighting the need for new therapeutic strategies

The Hippo signaling pathway regulates cell proliferation and survival through the transcriptional co-activator YAP1

Format

PDF

Size

1 poster

City

San Antonio, Texas

Gene Expression and Apoptotic Responses to Panobinostat Treatment and YAP Knockdown in Ewing Sarcoma Cells

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