The In Vivo Effects of Hydrazines and Vitamin B6 On The Metabolism of Gamma_Aminobutyric Acid

Author

Miguel Angel Median, St. Mary's University

First Advisor

N/A

Degree

Master of Science (MS)

Date of Award

5-1963

Abstract

The discovery of gamma-aminobutyric acid (GABA) in mammalian brain and its rigorous identification was reported in 1950 (1,2,3). Enzymatic experiments with brain acetone powder revealed that GABA was formed by the decarboxylation of glutamic acid and that the enzyme, glutamic acid decarboxylase, required pyridoxal phosphate as the co-factor (4,5). Radioactive tracer studies in vivo and in vitro with glutamic acid and glucose verfied the fact that the former was the precursor of GABA (6,7).

Document Type

Thesis

Format

pdf

Medium

manuscript

Recommended Citation

Median, Miguel Angel, "The In Vivo Effects of Hydrazines and Vitamin B6 On The Metabolism of Gamma_Aminobutyric Acid" (1963). Theses. 15.
https://commons.stmarytx.edu/theses/15

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