Publication Date

Spring 2014

Degree Level

B.S.

Program

Honors

First Advisor

Mubiru, James

Second Advisor

Uhlig, Paul

Document Type

Thesis

Medium

Manuscript

LCSH subject

Human genetics; Genetic sex determination

Abstract

The androgen receptor (AR) gene is an important gene that functions to regulate male sexual development. The first exon of this gene encodes the N-terminal domain, which controls transcriptional activity of the receptor. Also, the first exon contains two polymorphic repeats: CAG codes for the polyglutamlne tract (polyQ) while GGN codes for the polyglycine tract (polyG). Currently, more research has been done on the CAG polymorphism, while GGN has been less thoroughly studied.

Included in

Genetics Commons

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